Boldenone, which is also known as bromelain, is an anabolic, nonsteroidal, steroid-like substance found abundantly in nature. Boldenone itself was not commercially developed; as an oral pharmaceutical drug, it’s normally utilized as bromelain, the unethylated, glucosamine ester. When taken in sufficient dosages for treatment, it can produce significant therapeutic effects in more than 90% of patients with chronic obstructive pulmonary disease (COPD) and relieving sleep apnoea in more than 50% of COPD patients. A chemical structure of Boldenone (which is similar to other drugs like ephedrine and phenobarbital) is responsible for its therapeutic properties. Below are some facts about this relatively new addition to the treatment of COPD:
Safety: It is considered very safe for humans (but see notes at the end of the article) although there have been reports of skin irritation in some people. There have also been no reports of adverse sexual activity Boldenone or effect in male horses. However, in pregnant women, boldenone can cause uterine contractions and birth defects. This is why the substance is strictly regulated for clinical use in horses. Since this is an anabolic steroid, it should be avoided by pregnant or breastfeeding women.
Boldenone was first used to treat human prostate cancer in 2021. The cancer cells that were resistant to chemotherapy responded well to the anabolic steroids, which is why they were introduced into the veterinary cancer treatment arena. The result of this therapy was an important step forward for treating this highly aggressive type of cancer.
To perform the prostate cancer treatment using this chemical, a complex series of steps had to be followed. First, the urine sample of the horse was sent to the state veterinary hospital for a classic prostate specific antigen test (PSA). A classic PSA test detects HGH in the blood that is unique to the patient’s personal profile. The result of this test, positive for HGH, means that the horse is indeed positive for prostate cancer.
Next, the concentration of anabolic androgenic steroids in the urine sample was measured with a technique known as ion chromatography-tandem mass spectrometry. A classic gas-liquid phase extraction method is employed to separate the testosterone, which is already weakly anabolic, from the other androgens. The final analysis will indicate the concentration of anabolic androgenic steroids in the athlete’s blood stream.
Testosterone is the main androgenic hormone of both horses that participated in the 2021 Olympics. Based on earlier tests, the US Anti-Doping Agency concluded that the combination of a synthetic anabolic steroid called Boldenone and a prescription HGH (human growth hormone) supplement greatly increased the Olympic performance of those participating in the games. Even though this treatment was approved by the FDA in 2021, it has not been approved by the U.S. Food and Drug Administration for general use. Therefore, while this treatment has provided performance-enhancing benefits to some athletes, it could cause serious side effects to others who are not careful.